I have an Imacon scanner myself, but I always scan as 16-bit tiffs. The way I see it, the FFF format is a detour, and will only create extra work for you. Lightroom cannot import these files, and you would need Imacon/Hasselblad software to convert them to TIFF. I also think there is a plugin for Photoshop that allows you to open FFF files, and save them as TIFF.
The important thing is to scan in 16-bit, and make sure that you get all the information in the negatives into the scan - i.e. capture all the shadow and highlight detail. You want a histogram with ample space at both ends, and this is usually achieved by zeroing out all settings in the scanning program. You probably also want to disable any sharpening - it's much better to do this in Lightroom.
If you have problems with clipped shadows or highlights when scanning as negative, try scanning as a positive, and invert the image in Photoshop. You can use Lightroom to invert, but it's a lot easier in Photoshop. If you don't have Photoshop, I would strongly recommend subscribing to the CC Photography Plan - Photoshop and Lightroom for $10 a month.
You will almost certainly need to do some retouching - removing dust and scratches in the scans, and Lightroom is not suited for this kind of work. LR does have a spot removal tool, but compared to Photoshop, it is awkward to use, and what's worse - if you have more than a few spots in an image, it will slow Lightroom down to a crawl, or it might stop working completely.
So I recommend that you first bring the image into Photoshop, where you do retouching, noise reduction (Photoshop's noise reduction is far superior to Lightroom's), and a rough image adjustment, so that it looks reasonably good.
Now is the time to import the image in Lightroom, where you can do the fine tuning.
Lightroom will treat TIFFs the same way it treats raw files. The original is never touched, the edits are stored as metadata in the catalog. You can also edit the original in Photoshop after it has been imported in Lightroom, if you need to.
Lightroom can import layered TIFFs, and although you cannot see the layers in Lightroom, the layers will still be there if you go back to Photoshop to edit.