P: Program error when saving, lag when zooming, changes not reflecting in document window (macOS)

I have a similar problem. I can't do my client work properly.

@JeffreyTranberry  what utter nonsense. hard to track....

i have 4 friends who have the same issues with PS.

how can such a buggy version  be released?

because adobe does no proper beta testing.

these errors are so obvious on so many system.... how can they be missed?

i am honestly sick of the excuses.

while adobe makes billions it cost creatives billions of dollars in lost work hours. 😞

This is really weird, but I followed the suggestion from this link to turn off all the layers, then save the file. That worked. But as soon as I turned all the layers back on, I couldn't save (because of a program error) again. So I turned them all off, then turned them back on one at a time and saved after each new layer was visible. This worked until I hit one single layer that triggered the error. (It was a raster layer - not a smart object, no masks, not a vector, no effects. It WAS using the layer below as a clipping mask - but no other layers being clipped had triggered the error ¯\_(ツ)_/¯). After deleting that layer and rebuilding it, I was able to save the document without a problem. 

@JeffreyTranberry

Same issue is happening with me, too. Using OS, tried pasting as Pixels from Illustrator and I am unable to merge layers, zoom in or save my file. 

Could I please be added to the initiative?

The same is happening to me. At first, my Photoshop was constantly crashing which I managed to resolve by uninstalling and reinstalling. But now every time I use it, the program error comes up... very frustrating.

Same problem. We had to flatten every layer in order to finally be able to save the file. Now all our layers are rasterized. Better than losing and rebuilding, but not acceptable with no patch before the holidays. OSX 10.15.4 / PS 22.1.0

We are open to a PS test build as we use this program daily and on large print files. Please advise when there is a patch or update to fix this. Thanks. 

Same problem. We had to flatten every layer in order to finally be able to save the file. Now all our layers are rasterized. Better than losing and rebuilding, but not acceptable with no patch before the holidays. OSX 10.15.4 / PS 22.1.0

We are open to a PS test build as we use this program daily and on large print files. Please advise when there is a patch or update to fix this. Thanks. 

Dear Jeffrey
Not just saving has problem, can't even merge.
Tried many things, on twitter I got response from AdobeCare and truly thankful for them and You for answer, seriously thanks.
But still, aside from reinstall I tried - I think - everything You or on twitter was mentioned.
renamed thus disabled the unified folder, hiding layer is not a solution bc I need them obviously, tried the preferences You mentioned.
Went back an earlier saving tried merge and got the problem.
Ok, it's a complex problem but why adobe don't have a simple change back solution, I must have to reinstall for an earlier version. (or maybe I'm mistaken and there is a way for switch back?)

*dralt  It's not a simple as you might think. We've collected a number of files and don't have any problems working on or saving the files that have been provided - except in one case where the preferences (machineprefs.psp) were in a weird state.

Have you tried the troubleshooting steps in my official answer (one of the steps is to restore prefs)?

Sent your name to be added. Thx.