P: Program error when saving, lag when zooming, changes not reflecting in document window (macOS)

I just opened PS this evening to work on some images.  Haven't used PS in a few weeks so I guess it updated since the last time I used it.  I am also getting a Program Error and can not flatten any layers or save.  Extremely frustrating. Help!

SAME! I just relaunched Photoshop 2020 and opened the file, turned on all my layers and saved... Voila... it worked... I certainly hope that's not a sign that 2020 is better than 2021!!!

Same problem running latest version and latest version of Windows with all up to date drivers.

I work mainly from Lightroom , create a duplicate copy and import edit into Photoshop.

Unable to save files, unable to flatten layers, This is a piss take when you spend a good hour on a piece of work and unable to save.

One work around I found, if this is how anyone else works is.

1. In lightroom, make another duplicate copy and edit that in Photoshop.
2. Now, you cannot select the layers you was working on and copy into the new import as you will get the same error,
3. Instead, highlight your layers and using the move tool drag them over to the new imported image and align them back up.
4. Now you will be able to save the file as normal.

My system if this helps anyone.

• Adobe Photoshop Version: 22.1.0 20201125.r.94 2020/11/25: 4b16c876033  x64
• Number of Launches: 93
• Operating System: Windows 10 64-bit
• Version: 10 or greater 10.0.18362.1110
• System architecture: AMD CPU Family:15, Model:1, Stepping:0 with MMX, SSE Integer, SSE FP, SSE2, SSE3, SSE4.1, SSE4.2, AVX, AVX2, HyperThreading
• Physical processor count: 16
• Logical processor count: 32
• Processor speed: 3493 MHz
• Built-in memory: 32696 MB
• Free memory: 17965 MB
• Memory available to Photoshop: 29941 MB
• Memory used by Photoshop: 60 %
• ACP.local Status:
•  - SDK Version: 1.34.1
•  - Core Sync Status: Reachable and compatible
•  - Core Sync Running: 4.3.71.1
•  - Min Core Sync Required: 4.3.28.24
• ACPL Cache Config:
•  - Time to Live: 5184000 seconds
•  - Max Size: 20480 MB
•  - Purge Percentage: 50%
•  - Threshold Percentage: 85%
•  - Purge Interval: 60 seconds
• Live Edit Client SDK Version: 3.77.11
• Native GPU: Disabled.
• Manta Canvas: Enabled.
• Alias Layers: Disabled.
• Modifier Palette: Enabled.
• Highbeam: Disabled.
• Image tile size: 1028K
• Image cache levels: 4
• Font Preview: Medium
• TextComposer: Latin
• "2.1"
• glgpu[0].IsIntegratedGLGPU=0
• glgpu[0].GLMemoryMB=8011
• glgpu[0].GLName="GeForce RTX 2070 SUPER/PCIe/SSE2"
• glgpu[0].GLVendor="NVIDIA"
• glgpu[0].GLDriverVersion="27.21.14.5638"
• glgpu[0].GLDriver="C:\Windows\System32\DriverStore\FileRepository\nvddsi.inf_amd64_adb04b114014caa9\nvldumdx.dll,C:\Windows\System32\DriverStore\FileRepository\nvddsi.inf_amd64_adb04b114014caa9\nvldumdx.dll,C:\Windows\System32\DriverStore\FileRepository\nvddsi.inf_amd64_adb04b114014caa9\nvldumdx.dll,C:\Windows\System32\DriverStore\FileRepository\nvddsi.inf_amd64_adb04b114014caa9\nvldumdx.dll"
• glgpu[0].GLDriverDate="20200914000000.000000-000"
• glgpu[0].GLRenderer="GeForce RTX 2070 SUPER/PCIe/SSE2"
• glgpu[0].HasGLNPOTSupport=1
• glgpu[0].CanCompileProgramGLSL=1
• glgpu[0].GLFrameBufferOK=1
• clgpu[0].CLPlatformVersion="OpenCL 1.2 CUDA"
• clgpu[0].CLDeviceVersion="1.2"
• clgpu[0].IsIntegratedCLGPU=0
• clgpu[0].CLMemoryMB=8589
• clgpu[0].CLName="GeForce RTX 2070 SUPER"
• clgpu[0].CLVendor="NVIDIA"
• clgpu[0].CLBandwidth=3.680000e+11
• clgpu[0].CLCompute=3775.294473
• clgpu[0].CLRawDeviceName=GeForce RTX 2070 SUPER
• clgpu[0].CLRawDeviceVendor=NVIDIA Corporation
• clgpu[0].CLRawPlatformName=NVIDIA CUDA
• clgpu[0].CLRawPlatformVendor=NVIDIA Corporation
• nativegpu[0].NativeName="7812:NVIDIA GeForce RTX 2070 SUPER"
• License Type: Subscription

It's been this way for me since December 13th for me, and I was working on Photoshop renders for my Industrial Design finals in college, which stinks.  

Here are my specs:

- Apple MacBook Air 2015

- MacOS Big Sur 11.0.1

- Adobe Photoshop 2021 

I've just sent it to your e-mail!

@wiliamjk Could you send me a copy of the problematic file? This would help us to triage. Sympa@adobe.com Thanks, Sympa. 

@JeffreyTranberry since the newest update I've been having this issue. It seems to be only PSDC files not local. I also can not export image, copy any work done on the file to a new one, or save as local or vise versa. I turned Generator off and it helped for a bit but started back up again when saved as cloud. I also did a insane work around which works about 40% of the time. 

same problem! Cannot save any of my work since updating to 2021

When trying to save a psd file, I get a message 'cannot save due to program error'. 

Same problem, windows 10 and ps 2021.