Creative Cloud - Spinning wheel of doom

Hi,

I have Creative Cloud installed on a Win7 x64 Ent machine (tried both our installer and the newest version from the Adobe website) however when I'm launching the application I cannot get any further than the initial splash screen, along with the Spinning loading wheel.

If I leave this to get on with itself after a good 15-20 minutes there is still no change, merely more spinning! Eventually after an unknown amount of time (I left the system idle in the hopes it would sort itself out), I was greeted by a message informing me that Creative Cloud was "missing or damaged" (screenshot attached).

I have tried the following to resolve:

     - Ran the "Repair" function in the provided window,

     - Clean install onto newly built OS,

     - Running the Adobe Cleaner utility,

     -  All of the suggested fixes @ Creative Cloud FAQ

     - Uninstalled our packaged version of the CC installer, removed all registry keys from machine relating to Adobe CC and reinstalled with Adobe's latest installer

Any help much appreciated.

Thanks,

Nick