I've installed twice, fails all encodes and seems to corrupt video drivers at times crashing browsers.  Reminded me of hardware fails.  Encoding would go the way to the end and fail near stitching.  
 
2025.3 runs without issue from system restore.
2025.4 fails all h264 encodes
 
Since Premiere, AE and AME all updated at the same time, I'm not sure which one, but it must share whatever the issue is as both AME and Premiere Pro Direct encodes fail.
 
Windows64, 14900k, 3080ti, SSD M2 gen5, 96gb RAM.  Latest video driver updates.