"How do other people get around this issue?" they get grumpy at YouTube and get used to it compensate by adding some saturation, which I think isn't the best idea because then you're adding a workaround while messing up your original file actually, those are the only two answers I have. Like I said, I don't find that I lose saturation, but instead get a small red shift, so I can't speak to your exact issue. Checking MBD and MRQ aren't going to help, but if you have a good GPU then MBD is actually going to be used anyway. Checking MRQ is going to slow your export down and you won't notice a difference unless you're scaling your footage to a different resolution. Alternatively, you could try another codec instead of the MainConcept one that Adobe licenses. x264 is an open source H.264 codec which is really great, especially for retaining quality at even smaller file sizes. Give it a whirl and see what happens (VideoLAN - x264, the best H.264/AVC encoder ).
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