Are you talking about unassigned frames? If so, be sure to place your cursor over the edge of the frame before pressing and dragging the mouse to move the objects. If you are referring to text or graphics frames which you can normally move from the middle, perhaps something is locked? You might try Object > Unlock all on Spread. If it's neither of these, a screen shot would be really helpful. You can add it to this thread by using the 7th button on the toolbar when you reply. As for erasing the preferences file, it's trickier than it sounds. Get your four fingers ready on your one hand, hovering over Shift, Control, Opt and Command. Double click the InDesign icon in the dock and then immediately press and hold down all four keys until it the following message appears. It usually takes me a few tries.
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