Might be a pretty Niche feature request, but its been bugging me for a while, that Im not able to manipulate the blending mode via expressions or keyframes.
In my specific case, I work with data driven animation and Im changing the color of a layer based on certain conditions. My layer has to be either Red, Green, Blue or Silhouette Alpha.
My workaround for now is creating an extra layer above my main layer, that has its blending mode to Silhouette Alpha and matte it to that layer. Then I add an expression to that layers opacity, to make it turn on/off based on the conditions.
Apart from my usecase I think it could also add a lot of creative flexibility being able to animate between all the different blending modes.