Hello! It's a bit late but I ran into this exact same problem AND FOUND the cause of it. I had three B&W photos in a 3oo page book whose PDF turned fine on the first opening, then on any subsequent, these images wehre inverted White&Black. All are PSD files. So, I re-openened each file, flattened all layers ... Same issue !!! Then I figured out that for only these images, the "content" was larger than the "frame". Instead of cropping the image under Photoshop, I got lazy and shrunk their frame on my pages. I've reopened each of them under Photoshop, cropping them to the exact part of the image I wanted to place. Now the exported PDF is fine. So. No probleme with shrinking or expanding an image. However, the image must exactly fit its frame (Command-Shift-Option-E, then Command-Option-C). Hope it helps others here. Rgds, Thierry
... View more